WB2442 Toward Evidence-Based Prevention & Diagnosis of NEC in the Neonate Course

Objectives:,• Recognize that the burden of necrotizing enterocolitis (NEC) as a disease is best addressed through prevention rather than response to often catastrophic complications ,• Discuss the suggested implications and potential impact of select neonatal intensive care unit practices on disease course and outcomes related to necrotizing enterocolitis (NEC) as a result of care provided to preterm neonates ,• Explain the significant role that ideal diagnostic and prognostic biomarkers could play in identifying and differentiating classical necrotizing enterocolitis (NEC) from other non-NEC conditions ,• Outline the challenges encountered in identification of ideal biomarkers and describe current findings regarding potential serum, urine, and fecal biomarkers ,• Summarize the transcriptomic, proteomic, and metabolomic studies described in the evaluation of potential markers for diagnosing NEC