Hematopoiesis is organized by Keystone Symposia on Molecular and Cellular Biology and will be held from Feb 25 - 28, 2024 at Keystone Conference Center, Keystone, Colorado, United States of America.
Research in the Hematology field has seen explosive growth within the last decade. It has been at the forefront of major revolutions in our understanding of stem cell biology, and the origins and treatment of disease, including advances in genome engineering, insights into the function of the non-coding transcriptome and epigenome, and next-generation sequencing for cancer diagnosis. Further, hematological cells have served as a testing ground for technological advancements such as therapeutic genome engineering and next-generation sequencing efforts for cancer diagnosis. Importantly, development of targeted small molecule therapeutics and the introduction of immune-based (cell) therapies have shown direct clinical benefits, whereas the global pandemic has highlighted the critical need to understand the impact of inflammatory stresses on hematopoietic cell fate.
The mission of the Keystone Symposium on “Hematopoiesis” is to bring together biochemists, geneticists, molecular biologists and clinicians to bridge recent insights into the basic principles and biological mechanisms that control developmental hematopoiesis, hematopoietic stem cell biology, cell fate control with the diagnosis, progression and treatment of aging and inflammatory conditions, and hematologic disorders and malignancies. This conference will highlight innovations in emerging technologies, including single cell multiomics and imaging approaches, which are poised to fundamentally change our understanding in blood development and homeostasis. The program will also feature emerging discoveries, such as insights into the role of clonal hematopoiesis that predisposes individuals to hematopoietic disease and leukemic transformation, and the promising potential to manipulate cells for therapeutic intervention. Finally, the event will provide a platform for investigators from across disciplines and around the globe to establish productive collaborations and stimulate new ideas to enable substantial progress and address ongoing challenges in the hematology field.
Additional details will be posted as soon as information is available.