2021 CPIP-C Case 3: Hematology – Absolute Eosinophilia: A Practical Approach
2021 CPIP-C Case 3: Hematology – Absolute Eosinophilia: A Practical Approach is organized by College of American Pathologists (CAP).
Launch Date: March 15, 2021
Expiration Date: March 14, 2024
Description:
Absolute eosinophilia can be seen in numerous benign and malignant conditions. Clonal eosinophilia is seen with several hematolymphoid neoplasms in the World Health Organization 2016 classification including the complex category “myeloid/lymphoid neoplasms with eosinophilia and gene rearrangement.” This activity describes a unique case of reactive eosinophilia due to parasitic infection followed by a pragmatic approach for the work-up of eosinophilia, including the appropriate application of molecular genetic studies for clonal eosinophilia.
Objectives:
As a result of participating in this activity, you should be able to:
• Describe the spectrum of eosinophilic disorders ranging from benign to neoplastic.
• Describe the pathogenesis of eosinophilia-associated clinical syndromes with emphasis on a life-threatening parasitic infection.
• List the World Health Organization-defined eosinophilic disorders with key diagnostic features.
• Develop an algorithmic approach for the evaluation of clonal eosinophilia.
• Describe principles of treatment and prognosis of myeloid/lymphoid neoplasm associated with eosinophilia and PDGFRA.