Origins of Ovarian Epithelial Cancer: Theoretical and Practical Aspects (Sep 18, 2021 - Sep 17, 2024)
Origins of Ovarian Epithelial Cancer: Theoretical and Practical Aspects is organized by Opus Medicus, Inc.
Course Dates:
Last Review Date: 18-Sep-2021
Expiration Date: 17-Sep-2024
Description:
This course will review evidence to support current concepts of the origin and development of ovarian epithelial carcinoma. It will discuss practical applications of these concepts to diagnosis, staging, and treatment.
Objectives:
• To update pathologists, oncologists, gynecologists and trainees on current concepts of the origins of ovarian and fallopian tube epithelial carcinoma.
• To discuss implications for clinical practice and surgical pathology.
Topics:
• Review of ovarian serous carcinoma.
• BRCA as a model for early ovarian cancer.
• Sectioning of the fallopian tube: the SEE-FIM Protocol.
• Early serous carcinoma in the fimbria.
• Serous tubal intraepithelial carcinoma (STIC).
• Early versus late STICs.
• Ovarian serous carcinoma associated with tubal intraepithelial carcinoma (TIC).
• Tubal intraepithelial carcinoma associated with primary peritoneal serous carcinoma.
• Pathways for the development of ovarian serous carcinoma
• p53 signature.
• Proliferative/expansile p53 signature .
• Tubal p53 Signature as a precursor to pelvic serous carcinoma.
• Li Fraumeni Syndrome.
• Secretory cell outgrowths in the fallopian tube (SCOUTs).
• Practice-relevant issues.
• Approach to tubal intraepithelial carcinoma.