Genomics in Autism Routine Clinical Care and Research
Genomics in Autism Routine Clinical Care and Research is organized by University of Florida (UF) Continuing Medical Education (CME).
Release Date: 25-04-2022
Expiration Date: 24-04-2025
Learning Objectives:
As a result of participation in this activity, participants should be able to:
• Recognize that a significant percentage (30-40%) of individuals with autism and related neurodevelopmental disorders (NDD) have an underlying rare genetic disease that can be identified by routine clinical genetic testing (microarray, exome sequencing, genome sequencing).
• Describe the value of identifying a specific genetic cause of a child’s NDD, including ending the diagnostic odyssey, establishing accurate recurrence risk for parents, informing prognosis and often directly impacting medical and educational management plans.
• Differentiate between the genetic concepts of incomplete penetrance and clinical variability as it applies to dimensional (quantitative) traits such as cognitive ability (e.g., IQ) and social behavior (e.g., SRS).
• Recognize the role of both rare genomic variants with large effect size and common genomic variants with individually small effect sizes but cumulatively large effects, as well as the interplay of these two classes of genomic variants (largely additive).
Requirements for successful completion: Certificates are awarded upon successful completion (80% proficiency) of the post-test.
Additional details will be posted as soon as information is available.